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RainDog

(28,784 posts)
10. More research is available on cannabis than many FDA-approved drugs
Sun Jun 15, 2014, 01:54 PM
Jun 2014
http://www.washingtonpost.com/national/health-science/fda-drug-approvals-based-on-varied-data-study-finds/2014/01/21/b12d0712-82be-11e3-8099-9181471f7aaf_story.html

The Food and Drug Administration must bless any new drugs as “safe and effective” before they wind up in pharmacy aisles or prescribed to patients. But the ways in which the agency arrives at those approvals “vary widely in their thoroughness,” according to an analysis by researchers at Yale University’s School of Medicine.

“Not all FDA approvals are created equally,” said Nicholas Downing, lead author of the study, which examined nearly 200 new drug approvals between 2005 and 2012.

Researchers found broad differences in the data it took to get a thumbs up from FDA. For instance, the agency required that many new drugs prove themselves in large, high-quality clinical trials. But about a third won approval on the basis of a single clinical trial, and many other trials involved small groups of patients and shorter durations. Only about 40 percent of approvals included trials in which the new drug was compared with existing drugs on the market.


For cannabis?

20,000 published studies or reviews in the scientific literature referencing the cannabis plant and its cannabinoids, nearly half of which were published within the last five years, according to a keyword search on PubMed Central, the government repository for peer-reviewed scientific research.

Of these, more than 100 are controlled clinical trials assessing the therapeutic efficacy of cannabinoids for a variety of indications.

A 2006 review of 72 of these trials, conducted between the years 1975 and 2004, identifies ten distinct pathologies for which controlled studies on cannabinoids have been published

In fact, a 2008 meta-analysis published in the Journal of the Canadian Medical Association reported that cannabis-based drugs were associated with virtually no elevated incidences of serious adverse side-effects in over 30 years of investigative use.

http://www.suntimes.com/news/otherviews/24615512-452/pot-holds-no-medical-mysteries.html#.U1nRFK1dXQU

So, since cannabis has more scientific validity than many FDA drugs, why didn't Mr. Murray write an editorial calling for the FDA to pull all those drugs from the marketplace? I bet some of them were even for "chronic pain."

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