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xocetaceans

(4,238 posts)
12. I can only guess your background absent such extending comments. There is no intent to demean it. This is not a...
Tue Jan 7, 2025, 02:43 PM
Jan 2025

competition of qualifications. Regardless, given the background you stated, you should have mostly no problem at all if any following what they are discussing re: epitopes, genomes, etc. It mostly requires understanding ideas related to viruses and their genomes at a schematic level, not at the level of their biochemical structure, though that is hinted at on occasion. (I only mention biochemistry in this manner because, though it is important to why things are the way they are, its inclusion might serve to obscure the over-arching discussion of what is happening at a more coarse-grained conceptual scale. It is not intended as a taunt. The more important structures for the purposes of their discussion are at the level of the virus and its genome.)

Regarding the earlier comment you made on contemporary data from China: what sort of current data are you suggesting that they obtain and what sort of sources would be sufficiently credible? Unless it is being suggested that some sort of Chinese whistleblower will come forth with a set of government documents outlining a direct sequence of events leading to the outbreak, it is hard to imagine what would be being sought. The data to which I am referring was collected in situ in Wuhan roughly five years ago. There is no contemporary form of that data and cannot be. So, I have no idea what sort of data you might wish to be collected.

I still highly recommend that you watch the linked video if you want to understand the state of the situation. Keep in mind how many died as a result of misinformed takes on vaccinology and virology. I would suggest that it is too important an issue to discard.

Lastly, regarding a comment on the most recent briefing on China (the one from 1/7/25): it is not strictly true that no vaccines have been "developed" for hMPV. (Also, I think you might have inadvertently fused RSV and hMPV into "RMPV" in your comment.) Sanofi Pasteur is working on one that is to be in testing:

Study to Evaluate the Safety and Immune Response of an Investigational Vaccine for the Prevention of RSV (Respiratory Syncytial Virus) and (hMPV) Human Metapneumovirus Infection in Participants Aged 60 to 75 Years

Study Overview

Brief Summary
VAV00039 is a first-in-human (FiH) study to assess the safety and immunogenicity (in adult participants aged 60-75 years) after a single injection of different dose formulations of an RSV/hMPV vaccine candidate and RSV vaccine.

Detailed Description
The duration of participation will be approximately 6 months for each participant.

Official Title
A Phase 1, Randomized, Modified Double-blind, Multi-center, Parallel Group, Multi-arm Study to Investigate the Safety and Immunogenicity of an RSV/hMPV Vaccine Candidate in Adult Participants Aged 60 to 75 Years

...

https://clinicaltrials.gov/study/NCT06583031?term=hMPV&rank=1


So, yes, there are no currently approved vaccines for hMPV as far as I know, but there is, at least, one candidate that has been developed and is to be in testing later this year.

If you ever want to check on what is being investigated or what is to be investigated, the US government clinical trials website is (at present anyway) a good source: https://clinicaltrials.gov/.

We'll have to see if that survives the Trump Administration.

Recommendations

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We are on the uptake with respiratory and flu here also. Historic NY Jan 2025 #1
I like his measured take GreatGazoo Jan 2025 #2
Human Metapneumovirus (HMPV) is not new. It circulates in the US and elsewhere in winter at same time as RSV, FLU hlthe2b Jan 2025 #3
So, is this guy another hack reporter pushing the "flat-earth" virology of the lab leak hypothesis at 4:47 in the video? xocetaceans Jan 2025 #4
Tony is not a hack reporter. TexasTowelie Jan 2025 #6
Check the data on your "engineered virus" statement. You don't really know that any better than he does. n/t xocetaceans Jan 2025 #7
Really? TexasTowelie Jan 2025 #8
My statement is not one of "either...or". My point is you have no data of "yours" it came from a lab. xocetaceans Jan 2025 #9
Thanks for providing a link, but I'm not going to watch a 55 minute video from a virology class lecture. TexasTowelie Jan 2025 #10
Reading your comment again, I wanted to add one other thing. TexasTowelie Jan 2025 #11
I can only guess your background absent such extending comments. There is no intent to demean it. This is not a... xocetaceans Jan 2025 #12
You are correct that I fused HMPV and RSV together--it looked odd when I was typing it but I didn't check my work. TexasTowelie Jan 2025 #13
I appreciate your comments. I think that I was fairly sharp-edged in a comment/reply to one of your posts a few years... xocetaceans Jan 2025 #14
I like this guy Easterncedar Jan 2025 #5
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