Welcome to DU! The truly grassroots left-of-center political community where regular people, not algorithms, drive the discussions and set the standards. Join the community: Create a free account Support DU (and get rid of ads!): Become a Star Member Latest Breaking News Editorials & Other Articles General Discussion The DU Lounge All Forums Issue Forums Culture Forums Alliance Forums Region Forums Support Forums Help & Search

xocetaceans

(4,238 posts)
14. Under President Obama, there was a pause on GOF research. That was lifted after NIH had completed its study of how to...
Fri Apr 18, 2025, 09:10 PM
Apr 2025

...safely perform GOF research. This was the notice from the NIH and what follows is a link to the P3CO from the Obama White House's archive.

December 19, 2017
NIH Lifts Funding Pause on Gain-of-Function Research

Today, the National Institutes of Health announced that it is lifting a funding pause dating back to October 2014 on gain-of-function (GOF) experiments involving influenza, SARS, and MERS viruses. GOF research is important in helping us identify, understand, and develop strategies and effective countermeasures against rapidly evolving pathogens that pose a threat to public health. The funding pause was lifted in response to today’s release of the Department of Health and Human Services Framework for Guiding Funding Decisions about Proposed Research Involving Enhanced Potential Pandemic Pathogens (link is external)(HHS P3CO Framework).

...

We have a responsibility to ensure that research with infectious agents is conducted responsibly, and that we consider the potential biosafety and biosecurity risks associated with such research. I am confident that the thoughtful review process laid out by the HHS P3CO Framework will help to facilitate the safe, secure, and responsible conduct of this type of research in a manner that maximizes the benefits to public health.

I would especially like to acknowledge the efforts of the National Science Advisory Board for Biosecurity and the National Academies of Sciences, Engineering, and Medicine(link is external) for their thoughtful deliberations on the issues surrounding this important area of research. The work of these committees was instrumental in guiding the United States Government in its job of creating rigorous policy that allows vital research to move forward.

Francis S. Collins, M.D., Ph.D.
Director, National Institutes of Health

https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-lifts-funding-pause-gain-function-research


HHS P3CO Framework (This is linked to the National Archive's website and has the January 2017 PDF from the Obama White House.)

If ones listens to what Dr. Baric had to say back in late 2014, it should be clear that what is referred loosely to as GOF research is a valuable tool for surveillance and for establishing treatments (see from 8:09 to 17:25 in the video, and take particular note of his last slide):



Which "most agree" do you mean? How about an actual citation which would support that claim that Wuhan should have been working in BSL-4?

Here, for example, is the policy of the CDC:


Laboratory Biosafety Guidelines for working with SARS-CoV-2

...

SARS-CoV-2 specific guidance

To determine appropriate biosafety mitigation measures, laboratories should perform an activity-specific comprehensive risk assessment that evaluates laboratory facilities, personnel and training, practices and techniques, safety equipment, engineering controls, and other risk mitigation measures. Biosafety professionals, laboratory management, and scientific and safety experts should be involved in the comprehensive risk assessment process.

At a minimum, BSL-2 facilities, practices, and procedures are recommended for diagnostic research, anatomic pathology, environmental, and virus propagation activities utilizing SARS-CoV-2. At a minimum, ABSL-2 is recommended for work with these viruses in animal models.

...

https://www.cdc.gov/covid/php/lab/index.html


As is clear from the CDC website, BSL-2 and ABSL-2 are noted as the minima, not BSL-4.

One other note is that your assertion of the statement "So Ralph Baric of UNC started coordinating with Wuhan." seems to be incorrect: the implication in your post is that that happened after and as a consequence of 2014's pause of GOF research, but as is noted in your later post in this thread:

" “In 2013, the American virologist Ralph Baric approached Zhengli Shi at a meeting. ...." "

Basically, between the nonspecific, hyperbolic terminology ("scary", "unknown", "severe", "weird" ) that is present in your posts in this thread and the factual inaccuracies that are also present ( "bio 4 (sic) labs", "he (Trump) reversed", "2014" ), it seems that you really have not followed what happened with the SARS-CoV-2 pandemic closely enough to comment in an informed manner about it. You cite nearly nothing and seem to write in such a way to provoke fear and conspiracy theory. If you are able to take the time to understand his presentation, taking the time to listen to Dr. Baric's presentation from 2014 in the above video might clarify the issue.

Recommendations

0 members have recommended this reply (displayed in chronological order):

Even if true WSHazel Apr 2025 #1
Obama stopped gain-of-function in US in 2014 womanofthehills Apr 2025 #8
Under President Obama, there was a pause on GOF research. That was lifted after NIH had completed its study of how to... xocetaceans Apr 2025 #14
Wiki - List of laboratory biosecurity incidents womanofthehills Apr 2025 #29
US Right to Know- says work done in bio labs 2 to save money womanofthehills Apr 2025 #31
Conservatives will always invent theories to demonize government. bucolic_frolic Apr 2025 #2
Trump is DETERMINED to rewrite history on COVID-19 NCDem47 Apr 2025 #3
Well the rna shared between the two SARS is actually somewhat low for a mutagenic virus. 58Sunliner Apr 2025 #4
Believe it or not, there is a field of study related to viral genealogy. PSPS Apr 2025 #7
I looked at the genealogy, % of shared rna between the two SARS, how they spread, symptoms, etc... 58Sunliner Apr 2025 #10
How does one look at any of the viruses in the family of SARS-CoV-2 and come away with the idea that DNA is involved? xocetaceans Apr 2025 #17
I acknowledged that Covid does not have dna. 58Sunliner Apr 2025 #21
Yes, that alteration in your post from DNA to RNA is now acknowledged. Other questions that need to be addressed... xocetaceans Apr 2025 #23
And so? Yes, they are related. That isn't the question or the debate. 58Sunliner Apr 2025 #27
Yes, have a nice day indeed. How you can understand articles like the ones to which you've linked and still have... xocetaceans Apr 2025 #28
Is the horse dead yet, lol. 58Sunliner Apr 2025 #32
It wasn't the first time a SARS virus got lab people sick womanofthehills Apr 2025 #30
Scary stuff. 58Sunliner Apr 2025 #33
Doubt if it was Russia womanofthehills Apr 2025 #9
Did they find the source? No. 58Sunliner Apr 2025 #11
Wow! From Nov 2015 Nature.com med journal womanofthehills Apr 2025 #12
That is interesting-I posted this below, which is also interesting. 58Sunliner Apr 2025 #20
The principal problem with your reply is that SARS-CoV-2 is an RNA virus. DNA is not even present. I guess you could... xocetaceans Apr 2025 #15
Some viruses do have some dna, but not Covid. What they do look for in dna extractions are the markers of the virus- 58Sunliner Apr 2025 #19
This propaganda replaced the original covid-19 government site - see the earlier thread below... bsiebs Apr 2025 #5
Fuck off, felon. Basso8vb Apr 2025 #6
A deflection from his own blame. yellow dahlia Apr 2025 #13
Thank you for that reminder. It is an important fact. xocetaceans Apr 2025 #16
I think about this almost every day. So many lives have been lost, and forever changed. yellow dahlia Apr 2025 #18
I do also think of it often. Trump badly mishandled his role as President during the pandemic. One should recall... xocetaceans Apr 2025 #24
The fact that Dr. Fauci is mentioned on the front page of that monstrosity, area51 Apr 2025 #22
fascists are really big on rewriting history Skittles Apr 2025 #25
This is why Malice in Blunderland fails to understand what 19 means. GreenWave Apr 2025 #26
Latest Discussions»Latest Breaking News»White House touts Covid-1...»Reply #14